Peripheral arterial disease in polymyalgia rheumatica

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Peripheral arterial disease in polymyalgia rheumatica

Patients with polymyalgia rheumatica have been shown to have an increased risk of peripheral arterial disease on longitudinal follow-up. Possible explanations for this include premature atherosclerosis related to chronic inflammation, as with other inflammatory rheumatological conditions. Alternatively, polymyalgia rheumatica can be associated with vasculitis, even in the absence of clinical gi...

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Increased risk of peripheral arterial disease in polymyalgia rheumatica: a population-based cohort study

INTRODUCTION The present study was conducted to determine whether patients with polymyalgia rheumatica (PMR) are at an increased risk of peripheral arterial disease (PAD). METHODS An inception cohort of all Olmsted County, Minnesota residents diagnosed with PMR between 1 January 1970 and 31 December 1999 was compared with non-PMR subjects (two for each PMR subject) from among residents. Both ...

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A disease activity score for polymyalgia rheumatica.

OBJECTIVE To develop a composite score for measurement of disease activity in polymyalgia rheumatica (PMR) and assess its internal and external validity. METHODS A PMR activity score (AS) was designed and assessed for internal and external validity in two patient cohorts: 57 international patients evaluated primarily for development of the PMR-AS at baseline, weeks 4 and 24; and for validatio...

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Subclinical vasculitis in polymyalgia rheumatica.

Polymyalgia rheumatica (PMR) is an inflammatory condition of the aging population characterised by pain, stiVness, and symmetrical involvement of shoulder and pelvic girdles. It has been proposed that the primary site of disease may reside outside the synovial joint, 2 but its aetiopathogenesis remains ill understood. There is good indirect evidence that vasculitis is important in the pathogene...

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Update on polymyalgia rheumatica.

Polymyalgia rheumatica is an inflammatory disease of unknown etiology affecting individuals aged fifty years and older, mainly of Caucasian ethnicity. Polymyalgia rheumatica is associated with giant cell arteritis more frequently than expected by chance alone. In both conditions, females are affected two to three times more often than males. The clinical hallmark manifestations of polymyalgia r...

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ژورنال

عنوان ژورنال: Arthritis Research & Therapy

سال: 2009

ISSN: 1478-6354

DOI: 10.1186/ar2685